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Filtered Search Results
MEDCHEMEXPRESS LLC A-803467 10MG
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501872292 A-803467 10MG
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MEDCHEMEXPRESS LLC CARDIOGENOL C HYDROCHLORIDE
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501872636 CARDIOGENOL C HYDROCHLORIDE
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MEDCHEMEXPRESS LLC SANGUINARINE CHLORIDE 5MG
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501874605 SANGUINARINE CHLORIDE 5MG
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Aobchem 3-Chloro-2-phenoxy-4-(trimethylsilyl)pyridine | 95% | C14H16ClNOSi | 1g
3-Chloro-2-phenoxy-4-(trimethylsilyl)pyridine | 95% | C14H16ClNOSi | 1g
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Sigma Aldrich Fine Chemicals Biosciences (4-Bromophenoxy)-tert-butyldimethylsilane 97% | 67963-68-2 | MFCD00239382 | 5ML
(4-Bromophenoxy)-tert-butyldimethylsilane 97% | Purity: 97% | Mol Wt: 287.27 | 67963-68-2 | MFCD00239382 | 5ML
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Medchemexpress LLC KU-57788 | 503468-95-9 | 100.0% | 413.49 | 1 ML
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KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. It acts as an NHEJ pathway inhibitor, and also inhibits PI3K and mTOR with IC50s of 5.0 μM and 1.7 μM, respectively.
- Highly potent and selective DNA-PK inhibitor (IC50 of 14 nM)
- NHEJ pathway inhibitor
- Inhibits PI3K (IC50 of 5.0 μM) and mTOR (IC50 of 1.7 μM)
- Inhibits the growth of liver cancer HepG2 cells dose- and time-dependently
- Reduces pDNA-PKcs (S2056) protein expression in liver cancer cells
- Affects DNA damage repair when double treated with 60Coγ IR
- Reduces the frequency of NHEJ and increases the rate of HDR following Cas9-mediated DNA cleavage
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Aobchem 4-Ethynyl-1 2-dimethoxybenzene | ≥95% | CAS 4302-52-7 | C10H10O2 | 5g
4-Ethynyl-1 2-dimethoxybenzene | ≥95% | CAS 4302-52-7 | C10H10O2 | 5g
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Aobchem 4-[4-(Pentyloxy)phenoxy]phenol | 95% | CAS 160530-82-5 | C17H20O3 | 250mg
4-[4-(Pentyloxy)phenoxy]phenol | 95% | CAS 160530-82-5 | C17H20O3 | 250mg
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Medchemexpress LLC D-64131 | 74588-78-6 | C16H13NO2 | 100 MG
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D-64131 is an orally active tubulin inhibitor with an IC50 of 0.53 μM for tubulin polymerization. It exhibits antimitotic activity and can be utilized for cancer research. It is antimitotic by binding to β-tubulin, destabilizing microtubules, and arresting mitotic cells in the M-phase. This compound inhibits the proliferation of tumor cells from various organs and tissues, including cytotoxicity against MDR/MRP tumor cell lines.
- Exhibits antimitotic activity
- Useful in cancer research
- Inhibits tumor cell proliferation
- Cytotoxic against MDR/MRP tumor cell lines
- Suppresses U373 proliferation and cell cycle
- Significantly inhibits tumor growth in human amelanoic melanoma xenograft models
- Possesses oral bioavailability
- Well tolerated at efficacious doses
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Medchemexpress LLC Prexasertib dimesylate (LY2606368 dimesylate) | 1234015-58-7 | 98.9% | 557.60 | 100 MG
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Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. It also inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). This compound causes double-stranded DNA breakage and replication catastrophe, leading to apoptosis, and demonstrates potent anti-tumor activity.
- Selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor.
- Inhibits CHK2 and RSK1.
- Causes double-stranded DNA breakage and replication catastrophe.
- Induces apoptosis.
- Shows potent anti-tumor activity.
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eMolecules 54924-78-6 | 5-BROMO-2-ETHOXYBENZAMIDE | AstaTech | MFCD07551819 | 244.088 | C9H10BrNO2 | 95.000 | CCOc1ccc(Br)cc1C(N)=O | 0.1g | 696739802
5-BROMO-2-ETHOXYBENZAMIDE | AstaTech | 54924-78-6 | MFCD07551819 | 244.088 | C9H10BrNO2 | 95.000 | CCOc1ccc(Br)cc1C(N)=O | 0.1g | 696739802
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Aobchem 3-((3-(Trifluoromethyl)phenoxy)methyl)benzoic acid | 95% | CAS 30082-44-1 | C15H11F3O3 | 1g
3-((3-(Trifluoromethyl)phenoxy)methyl)benzoic acid | 95% | CAS 30082-44-1 | C15H11F3O3 | 1g
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Medchemexpress LLC Beta-asarone (standard) | 5273-86-9 | 208.25 | 5 MG
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Beta-asarone is an orally active and BBB-penetrable anti-inflammatory and neuroprotective agent, which is the major ingredient of Acorus tatarinowii Schott. It can protect nerve cells from apoptosis and autophagy, inhibit expression of α-synuclein, and provides myocardial protection. Beta-asarone can be used in the study of neurological and cardiovascular diseases.
- Orally active
- BBB-penetrable anti-inflammatory and neuroprotective agent
- Protects nerve cells from apoptosis and autophagy
- Inhibits α-synuclein expression
- Offers myocardial protection
- Useful for studying neurological and cardiovascular diseases
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Aobchem 3-((3-(Trifluoromethyl)phenoxy)methyl)benzoic acid | 95% | CAS 30082-44-1 | C15H11F3O3 | 5g
3-((3-(Trifluoromethyl)phenoxy)methyl)benzoic acid | 95% | CAS 30082-44-1 | C15H11F3O3 | 5g
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eMolecules Trimetazidine dihydrochloride | 13171-25-0 | MFCD00243086 | 25g
Matrix Scientific | Trimetazidine dihydrochloride | 25g | 389717704 | 12231 | 95.000 | 13171-25-0 | MFCD00243086 | 339.260 | C14H24Cl2N2O3
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